Fluticasone furoate: A new intranasal corticosteroid
نویسندگان
چکیده
منابع مشابه
Fluticasone Furoate, a Novel Inhaled Corticosteroid, Demonstrates Prolonged Lung Absorption Kinetics in Man Compared with Inhaled Fluticasone Propionate
BACKGROUND Fluticasone furoate (FF; GW685698) is a novel inhaled corticosteroid that is active at 24 h and under development for once-daily administration in combination with the long-acting β(2)-adrenoceptor agonist vilanterol (GW642444) for chronic obstructive pulmonary disease and asthma. In vitro studies examining the respiratory tissue-binding properties of corticosteroids showed FF to hav...
متن کاملSeasonal allergic rhinitis: fluticasone propionate and fluticasone furoate therapy evaluated
Seasonal allergic rhinitis (SAR) is increasing in prevalence such that 1 in 4 persons is affected in the UK. It represents a considerable burden of disease since in a significant proportion of individuals the severity of nasal-ocular symptoms has an important effect on daily activity, performance and quality of life. Intranasal steroids (INS) form the mainstay of treatment, having been shown in...
متن کاملFluticasone furoate/fluticasone propionate – different drugs with different properties
The similarity in the names of the recently introduced intranasal glucocorticoid fluticasone furoate (FF; Veramyst®, GlaxoSmithKline/Avamys®, GlaxoSmithKline UK, Uxbridge, UK) and the earlier fluticasone propionate (FP; Flonase®/Flixonase®, GlaxoSmithKline) has led many to assume that the two compounds have the same active principle (fluticasone) (e.g. 1, 2). This has been compounded by FP comm...
متن کاملFluticasone furoate nasal spray: Profile of an enhanced-affinity corticosteroid in treatment of seasonal allergic rhinitis
Of the classes of pharmacotherapy for seasonal allergic rhinitis, intranasal corticosteroids are the preferred treatment and are recommended in practice guidelines as first-line pharmacotherapy for rhinitis with prominent nasal congestion. The enhanced-affinity intranasal corticosteroid fluticasone furoate nasal spray (GW685698X), is one of the newest additions to the armamentarium for allergic...
متن کاملSystemic safety of fluticasone furoate/vilanterol combination.
The recent article by Busse et al on the safety of fluticasone furoate/vilanterol combination (FF/VI) in asthma reported no significant changes in geometric mean 24 h urinary cortisol (24UC) compared with baseline, perhaps giving a false impression that FF is devoid of systemic adverse effects. The interpretation of these data should be put in context of the patients who were already taking inh...
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ژورنال
عنوان ژورنال: Journal of Postgraduate Medicine
سال: 2012
ISSN: 0022-3859
DOI: 10.4103/0022-3859.93260